Community characteristics, like neighborhood stability, play a role in modulating genetic influences on alcohol consumption 16. Exposure to positive environments, such as supportive social networks and engaging activities, tends to dampen the expression of genetic predispositions related to alcohol use. Conversely, other variants may increase the risk of developing alcohol use disorder. The body’s ability to metabolize alcohol efficiently is a significant factor in alcohol tolerance and dependence. Understanding these hereditary risks can aid in developing prevention and treatment strategies.
Can You Test Your Genes For Addiction Risk?

According to the findings, 8.9 percent of the fathers and 1.6 percent of the mothers who gave their offspring up for adoption had been hospitalized for alcoholism. Therefore, if alcoholism is genetically influenced, then adoptees as a group would be at higher risk than the general population and would have elevated rates of alcoholism. The higher genetic risk among heroin addiction adoptees is a recurrent finding in the major adoption studies and should be taken into consideration when analyzing results. The first adoption-study evidence for an important genetic contribution to alcoholism risk was produced in Scandinavia.
- To learn more about how Nebula Genomics reports genetic variants in the table above, check out the Nebula Research Library Tutorial.
- Until we get there, research will continue focusing on identifying genetic variants and possible mechanisms behind risk.
- The World Health Organization (WHO) estimates that in 2016, alcohol was tied to 3 million deaths worldwide, and alcohol abuse is linked to 5.1 percent of disease globally.
- The journal Genes, Brain and Behavior publishes that this gene has been linked to a heightened risk of alcoholism.
- Alcohol intolerance is mostly genetic and especially common among people of East Asian descent.
- In contrast, children who grew up with parental support and community resources have a lower risk of developing an alcohol addiction.
Core Resource information on genetic vulnerability to AUD

Figure 1 illustrates the conceptual divide between biological and statistical epistasis that is important to understand in order to make biological inferences from statistical results (Moore and Williams 2005). This website is now operated by Northeast Recovery, L.L.C, a new and independent health treatment and recovery organization licensed in Massachusetts.It is not affiliated with or operated by ARK Behavioral Health. Published today in Nature Mental Health, the study was led by researchers at the Washington University in St. Louis, along with more than 150 coauthors from around the world. The Reframe app equips you with the knowledge and skills you need to not only survive drinking less, but to thrive while you navigate the journey. Our daily research-backed readings teach you the neuroscience of alcohol, and our in-app Toolkit provides the resources and activities you need to navigate each challenge. If you think of addiction as a weakness, you’ll paint yourself into a corner that you can’t get out of.
The Brain’s Role
Recognizing a hereditary predisposition to alcohol use disorder is the first step in breaking the cycle of familial alcoholism. Collectively, these protective factors play a vital role in preventing alcohol misuse. Healthy coping strategies 17 and skills development are crucial in lowering the risk of alcohol misuse. Seeking help for alcoholism is a brave and crucial step towards a healthier, more fulfilling life.
On the flip side, a person with no genetic history may still become addicted due to untreated trauma or mental health conditions. Research shows is alcoholism a genetic disease that there is a hereditary factor in the development of alcohol use disorders (AUDs). People who grew up with family members who struggled with alcohol addiction also have a higher risk of developing it.
